03/07/2025
Herpes Simplex is deemed one of the most common Sexually Transmitted Diseases, with about 3.8 billion people under age 50 having HSV-1 and about 520 million people aged 15-49 having HSV-2. The way this virus infects us is fascinating as it lays dormant in our body for long periods, asymptomatic, only to spring up and cause episodes of genital or oral herpes breakouts that primarily include painful blisters showing up around or on the lips or genitals. The infection is not severe, and its recurrence can be controlled. Herpes is no more than a periodic nuisance in one's life if one has a healthy immune system. However, HSV-2 may increase the chance of acquiring and transmitting HIV infection. Therefore, it is vital to handle outbreaks of this virus with care. Valtrex 500mg Tablets do an excellent job of managing symptoms of herpes. In this blog, we will learn more about the Herpes Simplex Virus and the uses and side effects of the Valtrex 500mg tablets.
Valtrex 500mg tablets contain valacyclovir as its active ingredient. It is majorly used to treat cold sores, shingles, and chickenpox (in children) and prevent the spread of genital herpes. This medication works by inhibiting an essential compound required for DNA formation in the virus, DNA polymerase. It inactivates the DNA polymerase, reducing the number of pathogens in the body and helping the immune system fight it off better. However, it cannot eliminate the virus from your entire body completely.
Ensure you are not allergic to any of the medication's ingredients. Read the entire ingredient list, including the inactive ingredients of the specific product dispensed to you.
If you are prescribed this medication to treat an outbreak of cold sores or other symptoms of a viral illness, it should be taken as soon as possible. It should be taken when you have any itching, burning, or sores.
Drink ample fluids when taking valacyclovir, as it may adversely affect your kidneys if you do not flush it out properly from your system.
People who are over the age of 65 are at a greater risk of developing side effects from the medication. Talk to your doctor about the risks before you take the medication.
Let your healthcare provider know if you have had any kidney problems, bone marrow transplant, have an HIV infection, or are immunocompromised in any manner so that they can adjust the medication accordingly or avoid it.
Some of the most common side effects of taking Valtrex 500mg tablets are:
Headache
Nausea
Stomach pain
Some serious side effects of this medication are:
A severe allergic reaction: Breathing problems, wheezing, trouble swallowing, throat closing up, swelling of the tissues of the face, itching, skin rash, hives, nausea, vomiting, dizziness, fainting, stomach cramps, joint pain.
Symptoms of kidney damage: Reduced need to urinate, swelling of lower limbs, confusion, nausea, seizures, and weakness.
Problems with your Central Nervous System: Feeling agitated or restless, hallucinations, confusion, trouble speaking, slurred speech, feeling shaky, seizures, sudden or severe mental or nervous system changes.
While the milder side effects of this medication are not a cause for concern, if they worsen or become bothersome, consider talking to your healthcare provider. If you experience severe side effects written above, seek medical help immediately and speak to your primary doctor about switching the medication. In case of an allergic reaction, call your local emergency service immediately.
Having the HSV-2 infection increases the risk of acquiring an HIV infection triples. Additionally, if you have HIV and HSV-2 infection, then you also have a higher chance of spreading the virus further and creating more complications. HSV-2 is the most common infection in people who already have the HIV infection.
Herpes Simplex can be very dangerous for people who are immunocompromised or have HIV infection alongside HSV. It can cause rare complications such as meningoencephalitis (inflammation of the meninges) and disseminated infection( an infection that spreads over to other parts of the body except for the infection site). It can also lead to encephalitis (inflammation of the active tissues of the brain) and keratitis(inflammation of the cornea of the eye).
This disease is birth-acquired and happens when an infant is exposed to the virus at birth. It is sporadic, occurring in about 10 per 100,000 births globally, but it can cause lasting neurological disability or death. The risk is the highest when the mother acquires the disease while she is pregnant or late into the pregnancy for the first time.
Here are some ways you can prevent the further spread of herpes if you are infected with the disease:
Avoid engaging in sexual activity when you have symptoms like blisters and sores present, as the virus is the most contagious during an active outbreak. You should also be careful without obvious symptoms as it can spread through asymptomatic shedding.
Use protection like condoms during intercourse as it can reduce the risk of transmission. However, the virus can still be transmitted through the parts that are not enclosed within the condom; the wise choice would be to abstain while you have any active outbreaks.
You should take antiviral medications such as Valtrex 500mg (valacyclovir) as a preventative measure to reduce the likelihood and severity of outbreaks, thereby reducing any transmission.
People with frequent outbreaks may benefit from suppressive antiviral therapy.
Limit your sexual partners and have an open conversation with them about your condition before any intimacy is initiated, as it may harm them. Avoid sharing intimate toys or other objects such as lip balms or razors.
Herpes Simplex Virus is a disease one must take seriously as it can result in fatal complications in people who may be immunosuppressed. Safe sex practices are a must, and the awareness of such practices should be propagated more throughout society and not seen as a taboo subject as it can save millions of lives and prevent many more people from contracting Sexually Transmitted Infections. Everyone should talk to their doctor to discuss some essential awareness about safe sex practices and how to keep oneself safe from these diseases. Antivirals such as Valtrex play an indispensable role in suppressing the illness in people who already suffer from it, making their lives easier and reducing the spread of the virus further into the population.
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