Premarin Vaginal contains a mixture of estrogen hormones Estrogen is a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body.
rnPremarin Vaginal is used to treat the vaginal symptoms of menopause such as dryness, burning, irritation, and painful sexual intercourse.
rnPremarin Vaginal may also be used for other purposes not listed in this medication guide.

The health and medical information provided here is for general purposes only and is not a substitute for the expertise and judgment of your physician, or other health care professional. It should not be understood to indicate that the use of this medicine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

Premarin Vaginal can cause birth defects in an unborn baby. Do not use Premarin Vaginal if you are pregnant. Do not use Premarin Vaginal if you have any of the following conditions: a history of heart attack, stroke, or blood clot (especially in your lung or your lower body), liver disease, abnormal vaginal bleeding, or a hormone-related cancer such as breast or uterine cancer.
rnLong-term treatment with conjugated estrogens may increase your risk of breast cancer, heart attack, or stroke. Talk with your doctor about your individual risks before using Premarin Vaginal long term, especially if you smoke or are overweight. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.
rnHave regular physical exams and self-examine your breasts for lumps on a monthly basis while using Premarin Vaginal.

Get emergency medical help if you have any of these signs of an allergic reaction to Premarin Vaginal: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Premarin Vaginal and call your doctor at once if you have any of these serious side effects:
rnchest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
rnsudden numbness or weakness, especially on one side of the body;
rnsudden headache, confusion, problems with vision, speech, or balance;
rnpain or swelling in your lower leg;
rnabnormal vaginal bleeding;
rnmigraine headache;
rnpain, swelling, or tenderness in your stomach;
rnconfusion, problems with memory or concentration;
rnjaundice (yellowing of the skin or eyes);
rnswelling in your hands, ankles, or feet; or
rna breast lump.
rnLess serious Premarin Vaginal side effects may include:
rnmild nausea, vomiting, bloating, stomach cramps;
rnbreast pain, tenderness, or swelling;
rnfreckles or darkening of facial skin;
rnincreased hair growth, loss of scalp hair;
rnchanges in weight or appetite;
rnproblems with contact lenses;
rnvaginal itching or discharge;
rnchanges in your menstrual periods, decreased sex drive; or
rnheadache, nervousness, dizziness, tired feeling.

Use Premarin Vaginal exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.
rnPremarin Vaginal is usually prescribed for only a short time and are most often used in a cycle, such as 3 weeks on followed by 1 week off. Some conditions require daily use and others require use only twice a week during the treatment period. Follow the directions on your prescription label.
rnTo apply Premarin Vaginal, use only the vaginal applicator provided. After each use, take the applicator apart and clean it with mild soap and warm water. Do not use hot or boiling water.
rnHave regular physical exams and self-examine your breasts for lumps on a monthly basis if you are using Premarin Vaginal long term.
rnIf you need to have any type of surgery, tell the surgeon ahead of time that you are using . You may need to stop using the medicine for a short time.
rnPremarin Vaginal can affect the results of certain medical tests. Tell any doctor who treats you that you are using Premarin Vaginal.
rnStore Premarin Vaginal at room temperature away from moisture and heat.